2008
Detección de episodios de hipoxia tisular isquémica mediante la monitorización neurofisiológica intraoperatoria combinada con la monitorización de la oxigenación tisular en la cirugía aneurismática
Autores: Arikan F, Vilalta J, Minoves T, Moncho D, Vilalta A, Noguer M, Ibarra B, Sahuquillo J
Publicación: Neurocirugia (Astur). 2008 Apr;19(2):113-120.
INTRODUCTION. Intraoperative neuromonitoring in aneurysm surgery can be very useful to determine inadequate positions of the vascular clip that cause partial or complete compromise of the cerebral sanguineous flow in the vascular territories irrigated by the arteries related to aneurysm. The direct visualization of these arteries after the application of the surgical clip can be insufficient in detecting this potentially detrimental situation. Knowing this circumstance on the onset would allow the neurosurgeon to correct it and to avoid, therefore, cerebral ischemic tissue hypoxia. We show the utility of the intraoperative monitoring of the oxygen tissue pressure (PtiO2) and the somatosensorial evoked potential (SSEP) for the detection of these situations with the example of a clinical case.
2008
Does multimodality monitoring make a difference in neurocritical care?
Autores: Sahuquillo J
Publicación: Eur J Anaesthesiol Suppl. 2008;42:83-6.
In spite of the many tools available for monitoring the central nervous system, there are no clinical trials which prove that continuous monitoring of any single variable in the intensive care unit has had any significant impact on the outcome of patients.
2008
Intracranial pressure monitoring with the Neurodur-P epidural sensor: a prospective study in patients with adult hydrocephalus or idiopathic intracranial hypertension
Autores: Poca MA, Martínez-Ricarte F, Sahuquillo J, Lastra R, Torné R, Armengol MS
Publicación: J Neurosurg. 2008 May;108(5):934-42
OBJECT: Continuous intracranial pressure (ICP) monitoring using an epidural sensor is a common technique used in selected neurosurgical patients. The aim of this study was to assess the safety and accuracy of the Neurodur-P epidural sensor in the clinical setting.
2008
Moderate and severe traumatic brain injury induce early overexpression of systemic and brain gelatinases
Autores: Vilalta A, Sahuquillo J, Rosell A, Poca MA, Riveiro M, Montaner J
Publicación: Intensive Care Med. 2008 Mar 19
OBJECTIVE: Recent experimental evidence suggests that matrix metalloproteinases (MMPs) are implicated in the pathophysiology of traumatic brain injury (TBI) by increasing blood-brain barrier permeability and exacerbating posttraumatic edema. We examined the acute profile of MMP-2 and MMP-9 in the plasma of patients with moderate or severe TBI and in the brain extracellular fluid (ECF).
2008
Intra-abdominal pressure: the neglected variable in selecting the ventriculoperitoneal shunt for treating hydrocephalus
Autores: Sahuquillo J, Arikan F, Poca MA, Noguer M, Martinez-Ricarte F
Publicación: Neurosurgery. 2008 Jan;62(1):143-9
OBJECTIVE: In the selection of a ventriculoperitoneal cerebrospinal fluid shunt, the intra-abdominal pressure (IAP) is traditionally neglected as a result of the idea that its value is close to 0 mmHg. Our aim was to explore the relationship between body mass index (BMI) and IAP with the goal of providing clinically relevant data that could help neurosurgeons to estimate IAP and select the appropriate shunt for patients with hydrocephalus and especially those with normal-pressure hydrocephalus syndrome.